Methods of controlling proliferation and differentiation of stem and progenitor cells
US7169605B2 · kind B2 · utility
14Cited by
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14Claims
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Key dates
| Filing date | Mar 4, 2003 |
| Grant date | Jan 30, 2007 |
| Priority date | — |
| Expiry date | Apr 14, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K35/28
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of ex-vivo expanding a population of stem cells, while at the same time inhibiting differentiation of the stem cells. The method comprises ex-vivo providing the stem cells with conditions for cell proliferation and with at least one copper chelator in an amount and for a time period for permitting the stem cells to proliferate and, at the same time, for reducing a capacity of the stem cells to differentiate
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