Patent · US Expired

Tetrapeptide inhibitors of β-secretase

US7169759B1 · kind B1 · utility

0Cited by
4References
111Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 15, 2000
Grant dateJan 30, 2007
Priority date
Expiry dateMay 17, 2021

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/07
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Statine-derived peptide inhibitors of the β-secretase enzyme are provided which are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of Aβ peptide in a mammal. The compounds of the invention provide useful methods of treatment by administration of these inhibitors to reduce Aβ peptide formation and pharmaceutical compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.