Patent · US Expired

Aryl substituted thiazolidinones and the use thereof

US7169782B2 · kind B2 · utility

43Cited by

7References

39Claims

0Family size

Assignee

Euro-Celtique S.A. · LU

Inventors

Qun Sun · Princeton, US
Donald J. Kyle · Yardley, US
Parviz Gharagozloo · Pennington, US
Ji Yang · Jingwei, CN

Key dates

Filing date	Jul 16, 2002
Grant date	Jan 30, 2007
Priority date	—
Expiry date	Jul 16, 2022

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates aryl substituted thiazolidinones of Formula I:or a pharmaceutically acceptable salt, or solvate thereof, wherein R1 and R2, are defined in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.