Patent · US Expired

Multi-parameter fluorimetric analysis in a massively parallel multi-focal arrangement and the use thereof

US7170598B2 · kind B2 · utility

24Cited by

5References

19Claims

0Family size

Assignee

DIREVO BIOTECH AG · DE

Inventors

Peter J. Walla · Braunschweig, DE
Andre Koltermann · Icking, DE
Ulrich Kettling
Mathias Scharte · Cologne, DE

Key dates

Filing date	Oct 17, 2003
Grant date	Jan 30, 2007
Priority date	—
Expiry date	Dec 23, 2024

Classification

Technology area (CPC G)Physics
CPC primaryG01N2021/1789
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method for analyzing properties of a sample by measuring fluorescence parameters in multiple foci, comprises the steps of splitting a collimated primary laser beam with a splitting device into at least two collimated secondary laser beams and deflecting the secondary laser beams such that they propagate at different propagation angles with respect to an optical axis of a focussing optic, focussing the secondary laser beams with the focussing optic into at least two volume elements in the sample, detecting light emitted from the volume elements with a detecting device, and evaluating the detected light for obtaining the properties to be analyzed. Furthermore, a device for implementing this method is described. The invention is particularly suited for high-throughput screening applications.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.