Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
US7172769B2 · kind B2 · utility
5Cited by
125References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 2000 |
| Grant date | Feb 6, 2007 |
| Priority date | — |
| Expiry date | Mar 18, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/58
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions are provided comprising one or more orally deliverable dose units, each comprising a selective cyclooxygenase-2 inhibitory drug of low water solubility in a therapeutically effective amount, wherein the drug is present in the form of solid particle, about 25% to 100% by weight of which are smaller than 1 μm. The compositions are useful in treatment or prophylaxis of cyclooxygenase-2 mediated conditions and disorders and have particular advantages where rapid onset of therapeutic effect is desired.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.