Methods and gel compositions for encapsulating living cells and organic molecules
US7172866B2 · kind B2 · utility
76Cited by
10References
11Claims
0Family size
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Key dates
| Filing date | Apr 2, 2002 |
| Grant date | Feb 6, 2007 |
| Priority date | — |
| Expiry date | Jul 29, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B60/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for encapsulating biologics within a hydrogel by using an aqueous solution of an isocyanate-functional hydrogel prepolymer which is mixed with an amount of biologics and an aqueous solution containing a dithiol crosslinking agent under physiological pH conditions. An additional bidentate crosslinking agent may be included. The product of such method may be a bioreactor or an assay device having a plurality or different biologics encapsulated at predetermined locations in a substrate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.