Substituted 3-cyanoquinolines as MEK inhibitors
US7173135B2 · kind B2 · utility
6Cited by
11References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 4, 2003 |
| Grant date | Feb 6, 2007 |
| Priority date | — |
| Expiry date | Jul 4, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention concerns quinoline derivatives of Formula (I) wherein each of Z1, m, R1, n, R3, Z2 and R14 have any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an anti-invasive or anti-proliferative agent in the containment and/or treatment of solid tumour disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.