Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals

US7173151B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Christian Stapper · Mainz, DE
• Heiner Glombik · Hofheim, DE
• Eugen Falk · Frankfurt am Main, DE
• Dirk Gretzke · Frankfurt am Main, DE
• Jochen Goerlitzer · Frankfurt am Main, DE
• Stefanie Keil · Frankfurt am Main, DE
• Hans-Ludwig Schaefer · Frankfurt am Main, DE
• Wolfgang Wendler · Bad Camberg, DE

Key dates

• Filing date: Feb 27, 2004
• Grant date: Feb 6, 2007
• Expiry date: Mar 31, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to arylcycloalkyl-substituted derivatives and to their physiologically acceptable salts and physiologically functional derivatives.What is described are compounds of the formula I,in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparation. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistence is involved.