Fusion proteins based upon somatostatin receptors
US7176187B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Feb 14, 2002 |
| Grant date | Feb 13, 2007 |
| Priority date | — |
| Expiry date | Mar 15, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to fusion proteins that can be used to assay gene transfer and expression both in vitro and in vivo. The fusion proteins contain a reporter protein, e.g. a somatostatin receptor, fused to a second protein, which may be a protein fusion tag. Alternatively, a fusion protein may be fused to a leader sequence. A leader sequence may localize an expressed protein, e.g. localize a fusion protein to the cell membrane. The invention includes nucleic acids encoding the fusion proteins and methods of assaying for gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.