Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis
US7176289B1 · kind B1 · utility
1Cited by
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10Claims
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Key dates
| Filing date | Mar 1, 2000 |
| Grant date | Feb 13, 2007 |
| Priority date | — |
| Expiry date | Mar 1, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of modulating angiogenesis in a vertebrate subject, the method comprising administering to the vertebrate subject an ECRTP/DEP-1 activity-modulating amount of a composition, whereby an ECRTP/DEP-1 within the vertebrate subject is contacted by the composition; and modulating angiogenesis through the contacting of the ECRTP/DEP-1 with the composition. Optionally, the composition includes a monoclonal antibody which preferentially binds ECRTP/DEP-1. Methods for screening for modulators of ECRTP/DEP-1 are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.