Process for preparing pharmaceutically active compounds
US7176311B2 · kind B2 · utility
1Cited by
15References
5Claims
0Family size
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Key dates
| Filing date | Jan 6, 2004 |
| Grant date | Feb 13, 2007 |
| Priority date | — |
| Expiry date | Jan 6, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for the preparation of Compounds of the formula (1):wherein R1, R2, R4 and R13 are as defined or a pharmaceutically or veterinarily acceptable salt or polymorph thereof, or a pharmaceutically or veterinarily acceptable solvate or pro-drug thereof: are potent and selective inhibitors of type 5 cyclic guanosine 3′,5′-monophosphate phosphodiestbrase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.