Bioreactor mediated recellularization of natural and tissue engineered vascular grafts
US7179287B2 · kind B2 · utility
24Cited by
8References
38Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 13, 2002 |
| Grant date | Feb 20, 2007 |
| Priority date | — |
| Expiry date | Jun 21, 2023 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S623/921
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Processes for producing a tissue graft comprising acellularizing or devitalizing a tubular tissue to produce a tissue matrix. The tissue matrix is then populated with at least some viable cells. The processing and the populating steps are performed in a closed system, such as a bioreactor. Tissue grafts produced using the inventive processes may be capable of withstanding physiological stress and strain conditions present at a site into which the tissue graft is implanted.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.