Materials and methods relating to fusion proteins an immune response
US7179471B2 · kind B2 · utility
1Cited by
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18Claims
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Key dates
| Filing date | Nov 20, 2001 |
| Grant date | Feb 20, 2007 |
| Priority date | — |
| Expiry date | Apr 13, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nucleic acid construct is provided for delivery into living cells in vivo for inducing an immune response in a patient to an antigen; the construct directing the expression of a fusion protein, said fusion protein comprising said antigen and an adjuvant sequence derived from a plant viral coat protein. Methods for making such constructs, and methods of using such constructs for the treatment of infectious disease, cancer and B cell malignancy, are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.