11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia
US7179802B2 · kind B2 · utility
6Cited by
1References
14Claims
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Key dates
| Filing date | Oct 30, 2003 |
| Grant date | Feb 20, 2007 |
| Priority date | — |
| Expiry date | Feb 9, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds having Formula I, including pharmaceutically acceptable salts, hydrates and solvates thereof:are selective inhibitors of the 11β-HSD1 enzyme. The compounds are useful for the treatment of diabetes, such as noninsulin-dependent diabetes (NIDDM), hyperglycemia, obesity, insulin resistance, dylsipidernia, hyperlipidemia, hypertension, Syndrome X, and other symptoms associated with NIDDM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.