Patent · US Expired

Method of treating of demyelinating diseases or conditions

US7179821B2 · kind B2 · utility

2Cited by
2References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 14, 2005
Grant dateFeb 20, 2007
Priority date
Expiry dateMar 14, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.