Zero-mode waveguides
US7181122B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 20, 2005 |
| Grant date | Feb 20, 2007 |
| Priority date | — |
| Expiry date | Dec 20, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9015
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.