β-lactamase inhibitors and methods of use thereof
US7183267B2 · kind B2 · utility
2Cited by
2References
21Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jun 10, 2004 |
| Grant date | Feb 27, 2007 |
| Priority date | — |
| Expiry date | Jun 10, 2024 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel non-β-lactam inhibitors of β-lactamases. In particular, the invention provides boronic acid-based compounds set forth in the specification. These compounds may be used with β-lactam antibiotics to bacterial infection, particularly, β-lactam-antibiotic-resistant bacterial infections. These compounds are also antibacterial agents by themselves. The invention further provides methods of using such compounds. Finally, the invention provides a pharmaceutical composition comprising these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.