Patent · US Expired

NF-κB inhibitors

US7183311B2 · kind B2 · utility

0Cited by

7References

23Claims

0Family size

Assignee

SmithKline Beecham Limited · US

Inventors

James Francis Callahan · Philadelphia, US
Yue Li · Shanghai, CN

Key dates

Filing date	Apr 11, 2003
Grant date	Feb 27, 2007
Priority date	—
Expiry date	Dec 28, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D333/78
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides novel compounds and methods for using them to treat diseases with aminothiophene inhibitors of IKK-β phosphorylation of IκB. In yso doing these aminothiophene inhibitors block pathological activation of transcription factor NF-κB in which diseases excessive activation of NF-κB is implicated.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.