Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (SCLC)
US7183389B2 · kind B2 · utility
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2Claims
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Key dates
| Filing date | Nov 1, 2001 |
| Grant date | Feb 27, 2007 |
| Priority date | — |
| Expiry date | Jun 26, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/77
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides new monoclonal antibodies and binding fragments thereof which recognize and immunoreact with cell surface antigens found on small cell lung cancer (SCLC) cells. The antibodies have tumor specificity and are useful for therapy, diagnosis, monitoring, detecting and imaging of SCLC disease and of patients having SCLC disease. The antibody-recognized SCLC-specific surface antigens can serve as targets for detecting, diagnosing, inhibiting or killing SCLC cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.