Site-specific, covalent bioconjugation of proteins
US7183392B2 · kind B2 · utility
5Cited by
5References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 27, 2001 |
| Grant date | Feb 27, 2007 |
| Priority date | — |
| Expiry date | Mar 27, 2021 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y30/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Heterofunctional crosslinking groups are provided having the formula:wherein W is a covalent core component; L1, L2 and L3 are independently linking groups; X is a non-covalent or reversibly covalent protein tag binder; Y is a activatable covalent linking group; and Z is a protected or unprotected covalent crosslinking group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.