Diastereoselective reductive amination process
US7183425B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jul 29, 2005 |
| Grant date | Feb 27, 2007 |
| Priority date | — |
| Expiry date | Aug 17, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention describes a reductive amination process whereby perfluorinated ketones or ketals are combined with α-aminoesters under basic conditions to form metal carboxylates. Diastereoselective reductions of the metal carboxylates enable access to two diastereomers, depending on the reducing conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.