Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
US7186397B2 · kind B2 · utility
2Cited by
19References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 30, 2000 |
| Grant date | Mar 6, 2007 |
| Priority date | — |
| Expiry date | Nov 27, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Diagnostic and therapeutic compositions in the form of complexes for enhancing transmembrane transport of a diagnostic or therapeutic agent and methods for their use. The complexes contain the α, γ, or bis isomers of folate receptor-binding analogs of folate, a metal chelated by a ligand, and in one embodiment, a chemotherapeutic agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.