Conformationally restricted polyamine analogs as disease therapies
US7186825B2 · kind B2 · utility
10Cited by
97References
20Claims
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Key dates
| Filing date | Jun 21, 2004 |
| Grant date | Mar 6, 2007 |
| Priority date | — |
| Expiry date | Jun 21, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.