Apolipoprotein A-L agonists and their use to treat dyslipidemic disorders

US7189689B2 · kind B2 · utility

Assignees

• Jean-Louis Dasseux · US
• Renate Sekul · DE
• Klaus Buttner · DE
• Isabelle Cornut · CH
• Gunther Metz · DE
• Jean Dufourcq · FR

Inventors

• Jean-Louis Dasseux · Mannheim, DE
• Renate Sekul · Ladenburg, DE
• Klaus Büttner · Epfenbach, DE
• Isabelle Cornut · Edingen-Neckarhausen, DE
• Günther Metz · Edingen-Neckarhausen, DE
• Jean Dufourcq · Pessac, FR

Key dates

• Filing date: Mar 15, 2002
• Grant date: Mar 13, 2007
• Expiry date: Aug 23, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.