Compositions for the treatment of pigmentation disorders and methods for their manufacture
US7189759B2 · kind B2 · utility
0Cited by
11References
8Claims
0Family size
Assignee
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Key dates
| Filing date | May 23, 2001 |
| Grant date | Mar 13, 2007 |
| Priority date | — |
| Expiry date | Jan 12, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K45/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention addresses the problem of excessive discoloration in hydroquinone compositions of a neutral pH. Antioxidants in the hydroquinone phase and inorganic or amino acyl cationic salts of acidic ascorbyl esters, preferably sodium metabisulfite and magnesium ascorbyl phosphate respectively, are effective in stabilizing such hydroquinone compositions, which are used in treatment of pigmentation disorders. Protected retinoid may be added to these compositions for additional skin benefit effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.