Thiomolybdate analogues and uses thereof

US7189865B2 · kind B2 · utility

Assignees

• Attenuon, LLC · US
• THE REGENTS OF THE UNIVERSITY OF MICHIGAN · US

Inventors

• Robert J. Ternansky · San Diego, US
• Andrew P. Mazar · San Diego, US
• Patricia Gladstone · San Diego, US
• Dimitri Coucouvanis · Ann Arbor, US
• Amy Allan · San Diego, US
• Sean O'Hare · San Diego, US
• Melissa Price · Irvine, US
• Steven Pirie-Shepherd · Irvine, US
• Fernando Donate · San Diego, US

Key dates

• Filing date: May 28, 2003
• Grant date: Mar 13, 2007
• Expiry date: Dec 8, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/088
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The current invention provides novel thiomolybdate derivatives, methods of making novel thiomolybdate derivatives, pharmaceutical compositions of novel thiomolybdate derivatives, methods of using novel thiomolybdate derivatives to treat diseases associated with aberrant vascularization, copper metabolism disorders, neurodegenerative disorders, obesity or NF-κB dysregulation and methods of using pharmaceutical compositions of thiomolybdate derivatives to treat diseases associated with aberrant vascularization, copper metabolism disorders, neurodegenerative disorders, obesity or NF-κB dysregulation.