Patent · US Expired

Porous membranes for use with implantable devices

US7192450B2 · kind B2 · utility

1,136Cited by
259References
28Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 22, 2003
Grant dateMar 20, 2007
Priority date
Expiry dateMar 23, 2025

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61L31/14
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A membrane for implantation in soft tissue comprising a first domain that supports tissue ingrowth, disrupts contractile forces typically found in a foreign body response, encourages vascularity, and interferes with barrier cell layer formation, and a second domain that is resistant to cellular attachment, is impermeable to cells and cell processes, and allows the passage of analytes. The membrane allows for long-term analyte transport in vivo and is suitable for use as a biointerface for implantable analyte sensors, cell transplantation devices, drug delivery devices, and/or electrical signal delivering or measuring devices. The membrane architecture, including cavity size, depth, and interconnectivity, provide long-term robust functionality of the membrane in vivo.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.