Methods for analyzing polynucleotide targets using tethered oligonucleotide probes
US7192707B2 · kind B2 · utility
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Key dates
| Filing date | Nov 6, 2003 |
| Grant date | Mar 20, 2007 |
| Priority date | — |
| Expiry date | Jan 28, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of analyzing a polynucleotide target involves incubating the target with an oligonucleotide probe, generally an array of immobilized oligonucleotide probes, to form a duplex, and using ligase or polymerase to extend one chain of the duplex. A point mutation or variable number tandem repeat section may be analyzed. Arrays of immobilized oligonucleotides are provided for use in the method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.