Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices
US7192769B2 · kind B2 · utility
52Cited by
10References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 31, 2002 |
| Grant date | Mar 20, 2007 |
| Priority date | — |
| Expiry date | Oct 12, 2023 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of antigen presenting cells and lymphoreticular stromal cells, and in the absence of exogenously added growth factors. The resulting lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.