Tripeptide and tetrapeptide sulfones
US7192918B2 · kind B2 · utility
3Cited by
9References
25Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 5, 2006 |
| Grant date | Mar 20, 2007 |
| Priority date | — |
| Expiry date | Jan 5, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Tripeptide and tetrapeptide sulfones, pharmaceutical compositions containing them, their pharmaceutical use, and their preparation, are disclosed. The compounds are useful in potentiating the cytotoxic effects of chemotherapeutic agents in tumor cells, selectively exerting toxicity in tumor cells, elevating the production of GM progenitors in bone marrow cells, stimulating the differentiation of bone marrow, mitigating the myelosuppressive effects of chemotherapeutic agents, and modulating hematopoiesis in bone marrow.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.