Benzothiazepine derivatives

US7192946B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Ingemar Starke · Gothenburg, SE
• Mikael Dahlstrom · Timrå, SE
• David Blomberg · Mölndal, SE
• Suzanne Alenfalk · Hultsfred, SE
• Peter Nordberg · Skara, SE
• Andreas Wallberg · Timrå, SE
• Stig Jonas Bostrom · Timrå, SE

Key dates

• Filing date: Aug 30, 2002
• Grant date: Mar 20, 2007
• Expiry date: Aug 30, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D281/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of formula (I), wherein variable groups are as defined within; pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia. Processes for their manufacture and pharmaceutical compositions containing them are also described