Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
US7195769B2 · kind B2 · utility
3Cited by
2References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 10, 2001 |
| Grant date | Mar 27, 2007 |
| Priority date | — |
| Expiry date | Oct 19, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the bioavailability of Rifampicin is enhanced by preventing its degradation caused by presence of Isoniazid. Rifampicin and/or Isoniazid may be present in delayed release and/or extended release form such that minimal amount of the drug is dissolved between pH 1 and 4. preferably delayed release of Rifampicin and/or Isoniazid is achieved by treating the drugs with pH sensitive polymers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.