Modification of cyclooxygenase and lipoxygenase activity with asteridae extracts and optionally boswellic acid
US7195790B2 · kind B2 · utility
9Cited by
10References
22Claims
0Family size
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Key dates
| Filing date | Dec 9, 2003 |
| Grant date | Mar 27, 2007 |
| Priority date | — |
| Expiry date | Dec 9, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K36/634
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Extracts from plants in the Asteridae subfamily, such as Carthamus tinctorious, are effective to selectively inhibit COX-2 activity and/or enhance COX-1 activity. When Asteridae extracts are combined with boswellic acid, the combination exhibits a synergistic inhibitory effect on both COX-2 and LO. Such extracts and combinations are used in methods of selectively inhibiting COX-2, inhibiting LO, and/or enhancing COX-1 activity as well as in the methods of treating conditions that would respond favorably to any of these effects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.