Indole derivatives as factor Xa inhibitors

US7196103B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Marc Nazare · Idstein, DE
• Volkmar Wehner · Bischofsheim a.d.Rhön, DE
• Kurt Ritter · Heidelberg, DE
• Volker Laux · Mainz, DE

Key dates

• Filing date: May 19, 2004
• Grant date: Mar 27, 2007
• Expiry date: May 27, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention is directed to the compound of formula I which is useful for inhibiting the activity of Factor Xa. The present invention is also directed to compositions containing said compounds, processes for their preparation, their use, such as for inhibiting the formation of thrombin or for therapeutically or prophylactically treating a patient suffering from, or subject to, or associated with a disease state associated with a cardiovascular disorder.