Drug sensitivity measuring method

US7198906B2 · kind B2 · utility

Assignees

• THE JIKEI UNIVERSITY SCHOOL OF MEDICINE · JP
• Japan as represented by Director General of National Institute of Advanced Industrial Science and Technology, Ministry of Economy, Trade and Industry · JP
• DAIKIN INDUSTRIES, LTD. · JP

Inventors

• Katsuhiko Machida · Tokyo, JP
• Sadayori Hoshina · Tokyo, JP
• Takashi Ushida · Yokohama, JP
• Junichiro Arai · Osaka, JP
• Hideo Katayama · Tsukuba, JP
• Chiaki Okumura · Ibaraki, JP
• Yoshihisa Amano · Nara, JP

Key dates

• Filing date: Mar 19, 2001
• Grant date: Apr 3, 2007
• Expiry date: Feb 26, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/18
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein is a method for determining the drug sensitivity of a microbe which comprises pouring a microbial suspension into each of the compartments or wells at a position which is in the vicinity of an electrode for measuring dissolved oxygen concentration, measuring current from each electrode at a second time interval for a third time period, each time is obtained based upon each of the measured currents at which the maximum current is obtained, obtaining each current value within a fourth time period which starts from the time at which the maximum current is obtained, detecting drug sensitivity based upon the variation condition of each current value during the fourth time period. The method allows rapid drug susceptibility measurements.