Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones

US7199265B2 · kind B2 · utility

Assignee

• Karo Bio AB · SE

Inventors

• Li Yi-Lin · Huddinge, SE
• Johan Malm · Älta, SE
• Chris Litten · Tumba, SE
• Ana Maria Garcia Collazo · Stockholm, SE
• Neeraj Garg · Tumba, SE

Key dates

• Filing date: Jun 15, 2001
• Grant date: Apr 3, 2007
• Expiry date: Feb 28, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/18
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of metabolism.