Patent · US Expired

Localized two-dimensional shift correlated MR spectroscopy of human brain

US7200430B2 · kind B2 · utility

57Cited by

8References

11Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Michael Thomas · Town of West Hartford, US
Kenneth Yue · Los Angeles, US

Key dates

Filing date	Mar 29, 2001
Grant date	Apr 3, 2007
Priority date	—
Expiry date	Oct 26, 2022

Classification

Technology area (CPC G)Physics
CPC primaryG01R33/4806
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A two-dimensional (2D) chemical shift correlated MR spectroscopic (COSY) sequence integrated into a new volume localization technique (90°-180°-90°) for whole body MR Spectroscopy. Using the product operator formalism, a theoretical calculation of the volume localization as well as the coherence transfer efficiencies in 2D MRS is presented. A combination of different MRI transmit/receive rf coils is used. The cross peak intensities excited by the proposed 2D sequence are asymmetric with respect to the diagonal peaks. Localized COSY spectra of cerebral frontal and occipital gray/white matter regions in fifteen healthy controls are presented.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.