Process for the production of proteins and the production of arrays of proteins

US7202055B2 · kind B2 · utility

Assignee

• ALTANA PHARMA AG · DE

Inventors

• Klaus Schafer · Oelde, DE
• Ingeborg Mühldorfer · Konstanz, DE

Key dates

• Filing date: Dec 19, 2001
• Grant date: Apr 10, 2007
• Expiry date: Jun 5, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/70
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Described is a novel process for the production of at least one protein of interest by secretion of the protein of interest from a pro- or eukaryotic host cell in a compartment system, which host cell is stably expressing a secretion system and capable of heterologous secretion of the protein of interest and which compartment system has at least a first and a second compartment and wherein the host cell is located in the first compartment and wherein the first and second compartment are separated from each other by a barrier, wherein the barrier is permeable for the secreted protein of interest, but not permeable for the host cell.