β-Cyclodextrin compositions, and use to prevent transmission of sexually transmitted diseases
US7202231B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 28, 2004 |
| Grant date | Apr 10, 2007 |
| Priority date | — |
| Expiry date | Dec 28, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/724
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods of reducing the risk of transmission of a sexually transmitted pathogen by contacting the pathogen or cells susceptible to infection by the pathogen with a β-cyclodextrin are provided. Methods for reducing the risk of transmission of a sexually transmitted pathogen to or from a subject by contacting the pathogen or cells susceptible to the pathogen in the subject with a pharmaceutical composition containing a β-cyclodextrin also are provided. Accordingly, pharmaceutical compositions, which include 1) a β-cyclodextrin, which is in an amount that blocks passage of the pathogen through lipid rafts in the membrane of a cell susceptible to the pathogen, and 2) a contraceptive, an agent for treating a sexually transmitted disease, a lubricant, or a combination thereof, are provided, as are composition formulated from a solid substrate that contains an amount of β-cyclodextrin useful for reducing the risk of transmission of a sexually transmitted pathogen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.