Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
US7202279B1 · kind B1 · utility
6Cited by
6References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1999 |
| Grant date | Apr 10, 2007 |
| Priority date | — |
| Expiry date | Feb 8, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0821
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective neuroprotective agents. Due to their strong central nervous system (CNS) activity, the compounds can be used to enhance memory and to treat a variety of neurological disorders. The compounds are particularly useful for treating neurological disorders caused by, or associated with, CNS trauma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.