Mass spectrometric analysis using nanoparticles

US7202472B2 · kind B2 · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Jürgen Schmucker · Stuttgart, DE
• Thomas Schiestel · Riegelsberg, DE
• Herwig Brunner · Stuttgart, DE
• Gunter Tovar · Stuttgart, DE

Key dates

• Filing date: Aug 16, 2002
• Grant date: Apr 10, 2007
• Expiry date: Mar 28, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/24
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention relates to an improved method for mass spectrometric analysis, in particular for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) using nanoparticles, where an analyte is added to a nanoparticle suspension, and the suspension containing the bound analyte is then deposited directly on a MALDI sample carrier and investigated by mass spectrometry, and to nanoparticles suitable for this method.