Multivalent neuraminidase inhibitor conjugates
US7205333B2 · kind B2 · utility
32Cited by
1References
39Claims
0Family size
Inventors
Key dates
| Filing date | Sep 7, 2001 |
| Grant date | Apr 17, 2007 |
| Priority date | — |
| Expiry date | Sep 22, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a multimeric compound or a pharmaceutically acceptable salt or derivative thereof which comprises three or more neuraminidase-binding groups attached to a spacer or linking group, in which the neuraminidase-binding group is a compound which binds to the active site of influenza virus neuraminidase, but is not cleaved by the neuraminidase. The invention also relates to processes for the preparation of the multimeric compound defined above, pharmaceutical compositions containing them or methods for the treatment and/or prophylaxis of a viral infection involving them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.