Patent · US Expired

Polyamino acid-catalyzed process for the enantioselective epoxidation of α,β-unsaturated enones and α,β-unsaturated sulfones

US7208447B2 · kind B2 · utility

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4References

2Claims

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Assignee

LANXESS Deutschland GmbH · DE

Inventors

Thomas Geller · Odenthal, DE
Christa Kruger · Hachenburg, DE
Hans-Christian Militzer · Odenthal, DE

Key dates

Filing date	Aug 25, 2004
Grant date	Apr 24, 2007
Priority date	—
Expiry date	Oct 11, 2025

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention relates to a novel process that makes it possible to epoxidize α,β-unsaturated enones or α,β-unsaturated sulfones with high conversions and enantiomeric excesses in a two-phase system without addition of water in the presence of an organic solvent, a base, an oxidant, a diastereomer- and enantiomer-enriched homo-polyamino acid that has not been separately preactivated as catalyst, and a specific phase-transfer catalyst as cocatalyst.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.