Malonic acid monomethyl derivatives and production process thereof
US7208621B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 14, 2006 |
| Grant date | Apr 24, 2007 |
| Priority date | — |
| Expiry date | Jul 14, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C67/343
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel monomethyl malonate derivative is represented by following Formula (I):wherein X is a halogen atom; and Me is methyl group. This compound can be prepared by the steps of (A) reacting a benzyl halide derivative represented by following Formula (II):wherein X and Y may be the same as or different from each other and are each a halogen atom, with dimethyl malonate in the presence of a base to yield a dimethyl malonate derivative represented by following Formula (III):wherein X and Me have the same meanings as defined above; and (B) hydrolyzing the dimethyl malonate derivative of Formula (III). The compound is useful in the production of an indanonecarboxylic acid ester having a halogen atom on the indanone ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.