Method of sequencing a nucleic acid
US7211390B2 · kind B2 · utility
446Cited by
131References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2004 |
| Grant date | May 1, 2007 |
| Priority date | — |
| Expiry date | Apr 13, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/0846
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and apparatuses for sequencing a nucleic acid. In one aspect, the method includes annealing a population of circular nucleic acid molecules to a plurality of anchor primers linked to a solid support, and amplifying those members of the population of circular nucleic acid molecules which anneal to the target nucleic acid, and then sequencing the amplified molecules by detecting the presence of a sequence byproduct such as pyrophosphate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.