Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
US7211414B2 · kind B2 · utility
472Cited by
2References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 3, 2001 |
| Grant date | May 1, 2007 |
| Priority date | — |
| Expiry date | Feb 17, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6853
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Nucleotide triphosphate probes containing a molecular and/or atomic tag on a a γ and/or β phosphate group and/or a base moiety having a detectable property are disclosed, and kits and method for using the tagged nucleotides in sequencing reactions and various assay. Also, phosphate and polyphosphate molecular fidelity altering agents are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.