Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin
US7211696B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Apr 23, 2003 |
| Grant date | May 1, 2007 |
| Priority date | — |
| Expiry date | Jul 23, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Dinitroaniline compounds useful for the treatment of diseases caused by parasitic protozoa in subjects in need of such treatment. The compounds are particularly useful in the treatment of leishmaniasis. The compounds are preferably less cytotoxic to normal cells than oryzalin. Also provided are methods of treating subjects having diseases caused by parasitic protozoa, preferably humans. The method comprising administering a therapeutically effective amount of a dinitroaniline compound of the present invention to a subject in need of such treatment
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.