Cell-based assay for the detection of toxic analytes
US7214505B1 · kind B1 · utility
1Cited by
9References
14Claims
0Family size
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Key dates
| Filing date | May 5, 2000 |
| Grant date | May 8, 2007 |
| Priority date | — |
| Expiry date | May 5, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/909
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Cell-based reagents and methods of using the reagents for detecting analytes are provided. The adsorbing of cells with signal-generating metabolic activity to solid supports has been found to improve the sensitivity of known cell based assays. Signal-generating cells adsorbed to a solid support are introduced to a test agent, and the measured decrease in metabolic signal provides a measure of the toxicity of the test agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.