Alleles of the mqo gene from coryneform bacteria

US7214526B2 · kind B2 · utility

Assignee

• Degussa AG · DE

Inventors

• Brigitte Bathe · Salzkotten, DE
• Stephan Hans · Osnabrück, DE
• Natalie Schischka · Bielefeld, DE
• Georg Thierbach · Bielefeld, DE

Key dates

• Filing date: Jan 18, 2006
• Grant date: May 8, 2007
• Expiry date: Jan 18, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/0006
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to mutants and alleles of the coryneform bacterium mqo gene which encodes malate quinone oxidoreductases which contain any amino acid apart from L-serine at position 111, or a comparable position, in the amino acid sequence, and to processes for fermentatively preparing amino acids, preferably L-lysine, L-tryptophan and L-proline, using bacteria which comprise these alleles.