Composite particles, derived conjugates, preparation method and applications
US7217457B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 6, 2002 |
| Grant date | May 15, 2007 |
| Priority date | — |
| Expiry date | Nov 22, 2022 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2998
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to composite particles comprising a hydrophobic polymer core and inorganic nanoparticles. Said hydrophobic polymer forms a polymer matrix inside which the inorganic nanoparticles are stabilized and distributed in a relatively homogenous manner. Said particles are at least partially surrounded by an amphophilic copolymer comprising a hydrophobic part and a hydrophilic part, said hydrophobic part being at least partially immobilized in the polymer matrix. The inventor also relates to the preparation method thereof, the conjugates comprising such particles and a ligand and the use of same in reactants and therapeutic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.